{"product_id":"human-plasminogen-activator-inhibitor-1-pai-1-elisa-kit-96t","title":"Human Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit , 96T","description":"\u003cp\u003eSerine protease inhibitor. Inhibits TMPRSS7 (PubMed: 15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed: 8481516, PubMed: 9207454, PubMed: 17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed: 9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed: 15001579, PubMed: 9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed: 18386027). It is involved in cellular and replicative senescence (PubMed: 16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed: 25808697, PubMed: 27046084).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592482304373,"sku":"BT-E1159Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-plasminogen-activator-inhibitor-1-pai-1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}