{"product_id":"human-presenilin-2-ps-2-elisa-kit-96t","title":"Human Presenilin 2, PS-2 ELISA Kit , 96T","description":"\u003cp\u003eProbable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak Channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis (PubMed: 16959576). Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria (PubMed: 21285369).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592479256949,"sku":"BT-E0980Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-presenilin-2-ps-2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}