{"product_id":"human-serine-arginine-rich-splicing-factor-1-sfrs1-elisa-kit-96t","title":"Human Serine\/Arginine-rich Splicing Factor 1, SFRS1 ELISA Kit , 96T","description":"\u003cp\u003ePlays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC\/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF\/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP\/NXF1 pathway.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592690479477,"sku":"BT-E6143Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-serine-arginine-rich-splicing-factor-1-sfrs1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}