{"product_id":"human-spry-domain-containing-socs-box-protein-1-spsb1-elisa-kit-96t","title":"Human Spry Domain-containing Socs Box Protein 1, SPSB1 ELISA Kit, 96T","description":"\u003cp\u003eSubstrate recognition component of a SCF-like ECS (Elongin BC-CUL2\/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed: 15601820, PubMed: 21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed: 21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed: 21199876).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592523067765,"sku":"BT-E3178Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-spry-domain-containing-socs-box-protein-1-spsb1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}