{"product_id":"il-12rbeta1-polyclonal-antibody-50ul","title":"IL-12RBeta1 Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe interleukin 12 receptor subunit beta 1 encoded by IL12RB1 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56513893368181,"sku":"BT-AP04439-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/products\/il-12rbeta1-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}