{"product_id":"impa1-rabbit-polyclonal-antibody-100ul","title":"IMPA1 Rabbit Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol| a precursor of phosphatidylinositol| and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1|4|5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1|3-diphosphate| myo-inositol-1|4-diphosphate| scyllo-inositol-phosphate| glucose-1-phosphate| glucose-6-phosphate| fructose-1-phosphate| beta-glycerophosphate| and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508982296949,"sku":"BT-AP10613-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/impa1-rabbit-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}