{"product_id":"jnk1-2-3-polyclonal-antibody-50ulbt-ap04705","title":"JNK1\/2\/3 Polyclonal Antibody, 50ul[BT-AP04705]","description":"\u003cp\u003eMitogen-activated protein kinase 8 encoded by MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56513987346805,"sku":"BT-AP04705-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/products\/jnk1-2-3-polyclonal-antibody-50ulbt-ap04705","provider":"LabCart Life Science","version":"1.0","type":"link"}