{"product_id":"lrrk1-polyclonal-antibody-50ul","title":"LRRK1 Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine\/threonine (Ser\/Thr) protein kinases. LRRK1 (leucine-rich repeat serine\/threonine-protein kinase 1), also known as RIPK6, Roco1 or KIAA1790, is a 2038 amino acid cytoplasmic protein that contains one protein kinase domain, four ANK repeats and 11 leucine-rich repeats and belongs to the Ser\/Thr protein kinase family. Using magnesium as a cofactor, LRRK1 catalyzes the ATP-dependent phosphorylation of target proteins. The gene encoding LRRK1, which is expressed as four alternatively spliced isoforms, is thought to be involved in the pathogenesis of Parkinson's disease.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514043085173,"sku":"BT-AP05082-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/products\/lrrk1-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}