{"product_id":"mcm4phospho-ser54-polyclonal-antibody-20ul","title":"MCM4(Phospho Ser54) Polyclonal Antibody, 20ul","description":"\u003cp\u003eThe protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC\/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512993919349,"sku":"BT-AP11176-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/mcm4phospho-ser54-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}