{"product_id":"mouse-interleukin-11-il-11-elisa-kit-96t","title":"Mouse Interleukin 11, IL-11 ELISA Kit, 96T","description":"\u003cp\u003eCytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 8913282). Also promotes the proliferation of hepatocytes in response to liver damage (PubMed: 22253262). Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers (PubMed: 10026196, PubMed: 23948300). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3 (PubMed: 23948300, PubMed: 22253262). The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592764338549,"sku":"BT-E0021Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/mouse-interleukin-11-il-11-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}