{"product_id":"mouse-t-cell-surface-glycoprotein-cd4-cd4-elisa-kit-96t","title":"Mouse T-cell Surface Glycoprotein Cd4, CD4 ELISA Kit, 96T","description":"\u003cp\u003eIntegral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II Peptides are derived from extracellular proteins while class I Peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation\/activation, cytokine expression and cell migration in a TCR\/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592852255093,"sku":"BT-E2507Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/mouse-t-cell-surface-glycoprotein-cd4-cd4-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}