{"product_id":"mouse-transcription-factor-sp1-sp1-elisa-kit-96t","title":"Mouse Transcription Factor Sp1, SP1 ELISA Kit, 96T","description":"\u003cp\u003eTranscription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4\/BRG1 on the c-FOS promoter Plays an essential role in the regulation of FE65 gene expression (By similarity). Positively regulates the transcription of the core clock component ARNTL\/BMAL1 (PubMed: 24030830). Plays a role in protecting cells against oxidative stress following brain injury by regulating the expression of RNF112 (PubMed: 27918959).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592853500277,"sku":"BT-E2519Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/mouse-transcription-factor-sp1-sp1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}