{"product_id":"mre11-polyclonal-antibody-100ulbt-ap05548","title":"MRE11 Polyclonal Antibody, 100ul[BT-AP05548]","description":"\u003cp\u003eMRE11A encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. MRE11A has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516570972533,"sku":"BT-AP05548-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/mre11-polyclonal-antibody-100ulbt-ap05548","provider":"LabCart Life Science","version":"1.0","type":"link"}