{"product_id":"nfκb-p105-p50phospho-ser337-polyclonal-antibody-50ulbt-ap05825","title":"NFκB-p105\/p50(Phospho Ser337) Polyclonal Antibody, 50ul[BT-AP05825]","description":"\u003cp\u003eThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515673063797,"sku":"BT-AP05825-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/nf%ce%bab-p105-p50phospho-ser337-polyclonal-antibody-50ulbt-ap05825","provider":"LabCart Life Science","version":"1.0","type":"link"}