{"product_id":"nf-kappa-b-p105-p50-monoclonal-antibody-50ulbt-mca0112","title":"NF Kappa B-p105\/p50 Monoclonal Antibody, 50ul[BT-MCA0112]","description":"\u003cp\u003eThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508582887797,"sku":"BT-MCA0112-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/products\/nf-kappa-b-p105-p50-monoclonal-antibody-50ulbt-mca0112","provider":"LabCart Life Science","version":"1.0","type":"link"}