{"product_id":"p300-polyclonal-antibody-100ulbt-ap06776","title":"p300 Polyclonal Antibody, 100ul[BT-AP06776]","description":"\u003cp\u003eEP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516644209013,"sku":"BT-AP06776-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/p300-polyclonal-antibody-100ulbt-ap06776","provider":"LabCart Life Science","version":"1.0","type":"link"}