{"product_id":"pa26-polyclonal-antibody-50ul","title":"PA26 Polyclonal Antibody, 50ul","description":"\u003cp\u003eSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514302935413,"sku":"BT-AP06869-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/pa26-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}