{"product_id":"pdh-e1-alpha-monoclonal-antibody-100ul","title":"PDH-E1 Alpha Monoclonal Antibody, 100ul","description":"\u003cp\u003eThe pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514648015221,"sku":"BT-MCA1012-100ul","price":270.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/pdh-e1-alpha-monoclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}