{"product_id":"phospho-arrestin-beta-1-s412-polyclonal-antibody-50ul","title":"Phospho-Arrestin-Beta-1 (S412) Polyclonal Antibody, 50ul","description":"\u003cp\u003eMembers of arrestin\/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514539422069,"sku":"BT-PHS00642-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/phospho-arrestin-beta-1-s412-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}