{"product_id":"phospho-atf-2-s62-polyclonal-antibody-20ul","title":"Phospho-ATF-2 (S62) Polyclonal Antibody, 20ul","description":"\u003cp\u003eATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508567093621,"sku":"BT-PHS00024-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/products\/phospho-atf-2-s62-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}