{"product_id":"phospho-bcr-y177-polyclonal-antibody-100ul","title":"Phospho-Bcr (Y177) Polyclonal Antibody, 100ul","description":"\u003cp\u003eA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. BCR, RhoGEF and GTPase activating protein has serine\/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for BCR.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516880990581,"sku":"BT-PHS00036-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/phospho-bcr-y177-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}