{"product_id":"phospho-catenin-beta-s552-polyclonal-antibody-100ul","title":"Phospho-Catenin-Beta (S552) Polyclonal Antibody, 100ul","description":"\u003cp\u003eCatenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516896096629,"sku":"BT-PHS01204-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/phospho-catenin-beta-s552-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}