{"product_id":"phospho-mlkl-s358-mouse-monoclonal-antibody6f8-100ul","title":"phospho-MLKL (S358) mouse Monoclonal Antibody(6F8), 100ul","description":"\u003cp\u003eThis gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain| however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516925522293,"sku":"BT-MCA1026-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/phospho-mlkl-s358-mouse-monoclonal-antibody6f8-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}