{"product_id":"rat-5-hydroxytryptamine-receptor-1a-htr1a-elisa-kit-96t","title":"Rat 5-Hydroxytryptamine Receptor 1A, HTR1A ELISA Kit, 96T","description":"\u003cp\u003eG-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592948527477,"sku":"BT-E1824Ra-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/rat-5-hydroxytryptamine-receptor-1a-htr1a-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}