{"product_id":"rat-podocalyxin-pcx-elisa-kit-96t","title":"Rat Podocalyxin, PCX ELISA Kit, 96T","description":"\u003cp\u003eInvolved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592987521397,"sku":"BT-E2204Ra-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/rat-podocalyxin-pcx-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}