{"product_id":"spta1-rabbit-polyclonal-antibody-20ul","title":"SPTA1 Rabbit Polyclonal Antibody, 20ul","description":"\u003cp\u003eSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton| and functions in the determination of cell shape| arrangement of transmembrane proteins| and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin| which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders| including elliptocytosis type 2| pyropoikilocytosis| and spherocytic hemolytic anemia. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512702873973,"sku":"BT-AP04870-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/spta1-rabbit-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}