{"product_id":"tirap-polyclonal-antibody-50ul","title":"TIRAP Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514474082677,"sku":"BT-AP09046-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/tirap-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}