{"product_id":"tporphospho-tyr626-rabbit-polyclonal-antibody-20ul","title":"TPOR(Phospho-Tyr626) Rabbit Polyclonal Antibody, 20ul","description":"\u003cp\u003eIn 1990 an oncogene| v-mpl| was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue| named| c-mpl| was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl| thrombopoietin| was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene| CD110| is a 635 amino acid transmembrane domain| with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic| emphasizing the important\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518140166517,"sku":"BT-AP13143-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/products\/tporphospho-tyr626-rabbit-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}