{"product_id":"wrn-rabbit-polyclonal-antibody-100ul","title":"WRN Rabbit Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism| including transcription| replication| recombination| and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity| and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70\/80 heterodimer in DNA end processing| this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome| an autosomal recessive disorder characterized by premature aging. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512724762997,"sku":"BT-AP05511-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/wrn-rabbit-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}