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SKU: E-AB-F1188E_50T-ES
APC Anti-Mouse FcεRIα Antibody[MAR-1], 50 T
FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Concentration:5 μL/Test
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Application:FCM
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Research Areas:Immunology;Innate Immunity
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Target Synonym:Fc-epsilon RI-alpha;FcERI;Fcer1a;High affinity immunoglobulin epsilon receptor subunit alpha
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Clonality:Monoclonal
Conjugation:APC
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