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SKU: E-AB-63107_200μL-ES
ARHGEF3 Polyclonal Antibody, 200 μL
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1 mg/mL
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Calculated Molecular Weight:36kDa/59kDa/60kDa/63kDa
Observed Molecular Weight:60kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:36kDa/59kDa/60kDa/63kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Metabolism;Signal Transduction
Species Reactivity:Human;Mouse
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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