SKU: E-AB-90587_60μL-ES

ASPH Polyclonal Antibody, 60 μL

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:21-34kDa/83-85kDa

Observed Molecular Weight:86kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:21-34kDa/83-85kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Neuroscience;Signal Transduction

Species Reactivity:Human

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Target Synonym:ASPH;AAH;BAH;CASQ2BP1;FDLAB;HAAH;JCTN;junctin

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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