SKU: E-AB-90007_60μL-ES

BCL2A1 Polyclonal Antibody, 60 μL

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Technical Specifications

Capacity:

Concentration:1mg/mL

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Calculated Molecular Weight:18kDa/20kDa

Observed Molecular Weight:Refer to figures

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:18kDa/20kDa

Dilution:IF 1:50-1:200

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Features and Capabilities

Application:IF

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Research Areas:Cancer; Cell Biology

Species Reactivity:Human

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Target Synonym:BCL2A1;ACC-1;ACC-2;ACC1;ACC2;BCL2L5;BFL1;GRS;HBPA1

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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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