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SKU: E-AB-66093_120μL-ES
CD46 Polyclonal Antibody, 120 μL
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1 mg/mL
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Calculated Molecular Weight:36kDa/39kDa/40kDa/41kDa/42kDa/43kDa/44kDa
Observed Molecular Weight:44kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:36kDa/39kDa/40kDa/41kDa/42kDa/43kDa/44kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer; Immunology
Species Reactivity:Human
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Target Synonym:AHUS2;MCP;MIC10;TLX;TRA2.10;CD46
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Buffer:PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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