SKU: E-AB-40578_100μL-ES

CXCL12/SDF1 Polyclonal Antibody, 100 μL

The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12α and SDF1/CXCL12β) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Calculated Molecular Weight:10kDa

Observed Molecular Weight:10kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:10kDa

Dilution:WB 1:2000-4000

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Application:WB

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Research Areas:Immunology;Microbiology;Cardiovascular

Species Reactivity:Human;Mouse;Rat

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Target Synonym:Cxcl12; SDF-1

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Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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