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SKU: AN003890P_25μg-ES
CXCL9/MIG Polyclonal Antibody(Capture/Detector), 25 μg
C-X-C motif chemokine ligand 9 (CXCL9, MIG) is a soluble chemokine expressed by multiple cell types, such as endothelial cells, monocytes, and tumor cells. The expression of CXCL9 is upregulated in response to proinflammatory cytokines, such as IFN-γ and TNF-α. (1,2). CXCL9 binds to CXCR3, a GPCR that is expressed on the surface of multiple populations of immune cells, particularly exclusively activated T lymphocytes (3). Binding of CXCL9 to CXCR3 promotes T cell chemotaxis and infiltration into sites of inflammation that form in settings such as viral infection and tumorigenesis (4-6). Research studies have demonstrated production of CXCL9 by tumor cells mediates tumor suppression through the recruitment of tumor antigen-specific T cells (7).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Dilution:ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL
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Features and Capabilities
Application:ELISA Capture/Detector
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Research Areas:Immunology
Species Reactivity:Human
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Target Synonym:crg;CXCL;SCYB;C-X-C Motif Chemokine;Small-Inducible Cytokine B;Chemokine(C-X-C motif) ligand;CXCL9;CMK;Humig;MIG;SCYB9;crg-10;Chemokine(C-X-C motif) ligand 9;C-X-C Motif Chemokine 9;Gamma-Interferon-Induced Monokine;Monokine induced by gamma interferon;Monokine Induced by Interferon-Gamma;Monokine Induced by Interferon-γ;Small-Inducible Cytokine B9
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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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Clonality:Polyclonal
Conjugation:Unconjugated
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