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SKU: E-AB-91948_200μL-ES
Enpp1 Polyclonal Antibody, 200 μL
This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:103kDa
Observed Molecular Weight:120kDa/170kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:103kDa
Dilution:WB 1:500-1:2000;IF 1:50-1:200
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Application:WB;IF
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Species Reactivity:Human;Mouse;Rat
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Target Synonym:Pca;ttw;twy;M6S1;NPP1;Npps;PC-1;Ly-41;Pca-1;Pdnp1;C76301;CD203c;E-NPP1;E-NPP 1;AI428932;4833416E15Rik;Enpp1
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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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