SKU: E-AB-65993_200μL-ES

EP300 Polyclonal Antibody, 200 μL

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:50-1:200

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Application:IHC

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Research Areas:Cancer; Epigenetics and Nuclear Signaling; Metabolism; Stem Cells

Species Reactivity:Human; Mouse; Rat

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Target Synonym:EP300;KAT3B;RSTS2;p300

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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