SKU: E-AB-90864_60μL-ES

GNRHR Polyclonal Antibody, 60 μL

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:27kDa/37kDa

Observed Molecular Weight:38kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:27kDa/37kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer;Neuroscience

Species Reactivity:Human;Mouse

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Target Synonym:GNRHR;GNRHR1;GRHR;HH7;LHRHR;LRHR

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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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