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SKU: E-AB-68294_60μL-ES
IGF2R Polyclonal Antibody, 60 μL
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Capacity:
Concentration:1 mg/mL
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Calculated Molecular Weight:274kDa
Observed Molecular Weight:274KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:274kDa
Dilution:WB 1:500-1:2000;IF 1:50-1:200
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Features and Capabilities
Application:WB;IF
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Research Areas:Cancer; Immunology; Signal transduction; Tags and Cell markers
Species Reactivity:Human; Mouse; Rat
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Target Synonym:IGF2R;CD222;CI-M6PR;CIMPR;M6P-R;M6P/IGF2R;MPR 300;MPR1;MPR300;MPRI
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Buffer:PBS with 0.01% thiomersal,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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