SKU: E-AB-67927_200μL-ES

PDE6A Polyclonal Antibody, 200 μL

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:99kDa

Observed Molecular Weight:120kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:99kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Signal Transduction; Neuroscience

Species Reactivity:Human; Mouse; Rat

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Target Synonym:PDE6A;CGPR-A;PDEA;RP43

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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