SKU: E-AB-66234_200μL-ES

PRKCZ Polyclonal Antibody, 200 μL

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:46kDa/56kDa/67kDa

Observed Molecular Weight:78kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:46kDa/56kDa/67kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer; Signal Transduction

Species Reactivity:Human; Mouse; Rat

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Target Synonym:PRKCZ;PKC-ZETA;PKC2

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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