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SKU: E-AB-91793_60μL-ES
PSMA/FOLH1 Polyclonal Antibody, 60 μL
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. [provided by RefSeq, Jul 2010]
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1mg/mL
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Calculated Molecular Weight:9kDa/12kDa/50kDa/78kDa/80kDa/82kDa/84kDa
Observed Molecular Weight:105KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:9kDa/12kDa/50kDa/78kDa/80kDa/82kDa/84kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:FGCP;FOLH;GCP2;GCPII;NAALAD1;NAALAdase;PSM;PSMA;mGCP;FOLH1
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Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.
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Clonality:Polyclonal
Conjugation:Unconjugated
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