SKU: E-AB-66586_200μL-ES

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TAZ Polyclonal Antibody, 200 μL

TAZ, also referred as WWTR1, is a transcriptional co-activator with a PDZ-binding motif that is regulated by its interaction with 14-3-3 protein. TAZ is expressed in many primary tumors, such as breast cancer, thyroid carcinoma, colorectal cancer, and glioma. TAZ has been reported to be one of the nuclear effectors of Hippo-related pathways that regulate organ size control, cancer stem cell (CSC) properties, and epithelial–mesenchymal transition (EMT). TAZ has been defined for its role in the nucleus, where it functions directly as a transcriptional regulator by interacting with several nuclear factors as Runx2/Cbfa1, NHERF-2, TEF-1, TBX5, PAX3, PAX8 and TTF-1.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IF 1:50-1:200

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Application:IF

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Research Areas:Cancer; Epigenetics and Nuclear Signaling; Stem Cells

Species Reactivity:Human; Mouse

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Target Synonym:BTK;AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;Bruton tyrosine kinase;TAZ;WWTR1

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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