BT LAB

SKU: BT-E5157Hu-96T

Human Cytochrome P450 11B1, Mitochondrial, CYP11B1 ELISA Kit, 96T

A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids (PubMed: 18215163). Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11-deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively (PubMed: 18215163). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed: 18215163).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:6.94ng/L

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Application:ELISA

Detection Target:CYP11B1

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Detection Range: 15-3000ng/L

Research Areas:Cardiovascular

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Assay Time:1h 30m

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