BT LAB

SKU: BT-E6417Hu-96T

Human Zinc Finger Protein Gli1, GLI1 ELISA Kit, 96T

Acts as a transcriptional activator (PubMed: 19706761, PubMed: 10806483, PubMed: 19878745, PubMed: 24311597, PubMed: 24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed: 2105456, PubMed: 8378770, PubMed: 24217340). Regulates the transcription of specific genes during normal development (PubMed: 19706761). Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed: 19706761, PubMed: 28973407). Plays a role in cell proliferation and differentiation via its role in SHH signaling (PubMed: 11238441, PubMed: 28973407). [Isoform 2]: Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:7.85ng/L

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Application:ELISA

Detection Target:GLI1

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Detection Range: 15-3000ng/L

Research Areas:Others

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