BT LAB

SKU: BT-E2018Mo-96T

Mouse Polycomb Complex Protein Bmi-1, BMI-1 ELISA Kit, 96T

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Application:ELISA

Detection Target:BMI1

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Detection Range: 0.05-30ng/ml

Research Areas:Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells

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Reactivity:Mouse

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Assay Time:1h 30m

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