BT LAB

SKU: BT-E6353Hu-96T

Human Tumor Susceptibility Gene 101 Protein, TSG101 ELISA Kit , 96T

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed: 22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed: 22315426).

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:7.86ng/L

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Application:ELISA

Detection Target:TSG101

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Detection Range: 15-3000ng/L

Research Areas:Cancer

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