BT LAB

SKU: BT-MCA0223-100ul

Bmi-1 Monoclonal Antibody, 100ul

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, IHC-p, IF, ICC, FCM, ELISA

Detection Target:BMI1

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Research Areas:Epigenetics and nuclear signaling; Cancer; Cell biology; Stem cells

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Reactivity:Human

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Clonality:Monoclonal

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Formulation:Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

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