BT LAB

SKU: BT-AP06228-50ul

FKBP1A/B Polyclonal Antibody, 50ul

The protein encoded by this gene is a member of the immunophilin protein family| which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels| and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse| deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants| encoding the same protein| have been identified. The human genome contains five pseudogenes related to this gene| at least one of which is transcribed.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:IHC-p, IF, WB

Detection Target:fkbp1a

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Research Areas:Immunology

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Reactivity:Human, Mouse, Rat

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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